GO:0000347 cellular_component THO complex
| PAG Title | GO:0000347 cellular_component THO complex |
| PAG ID | TAX013377 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. |
| Species | Homo sapiens |
| nCoCo Score | 1,745 |
| Base PAG ID | TAX013377 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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